Abed, A., Vaseghi, G., Jafari, E., Fattahian, E., Babhadiashar, N. and Abed, M. (2014). Echium Amoenum Fisch. Et Mey: A Review on its Pharmacological and Medicinal Properties. Asian Journal of Medical and Pharmaceutical Research, 4: 21-23.
Adam, F.I. M. and El-Ashry, Z.M. (2010). Evaluation of genotoxicity of 4-n-Nonylphenol using Vicia faba L. Journal of Biological Sciences, 10: 368-372. https://doi.org/10.3923/jbs.2010.368.372
Akinboro, A. and Bakare, A.A. (2007). Cytotoxic and genotoxic effects of aqueous extracts of five medicinal plants on Allium cepa Linn. Journal of Ethnopharmacology, 112: 470-475. https://doi.org/10.1016/j.jep.2007.04.014
Askin Celik, T. and Aslanturk, O.S. (2007). Cytotoxic and genotoxic effects of Lavandula stoechas aqueous extracts. Biologia, 62: 292-296. https://doi.org/10.2478/s11756-007-0051-2
Askin Celik, T. and Aslanturk, O.S. (2010). Evaluation of Cytotoxicity and Genotoxicity of Inula viscosa Leaf Extracts with Allium Test. Journal of Biomedicine and Biotechnology, 2010: 189252. https://doi.org/10.1155/2010/189252
Askin Celik, T.A. and Aslanurk, O.S. (2009). Investigation of cytotoxic and genotoxic effects of Ecballium elaterium juice based on Allium test. Methods and Findings in Experimental and Clinical Pharmacology, 31: 591-596. https://doi.org/10.1358/mf.2009.31.9.1434629
Aslantürk, O.S. (2018). In vitro cytotoxicity and cell viability assays: Principles, advantages, and disadvantages. In: Larramendy, M. and Soloneski, S. (Eds.), Genotoxicity: A predictable risk to our actual world, 2nd ed., pp. 64-80. Intech Open Limited, London, UK. https://doi.org/10.5772/intechopen.71923
Azizi, H., Ghafari, S., Ghods, R., Shojaii, A., Salmanian, M. and Ghafarzadeh, J. (2018). A review study on pharmacological activities, chemical constituents, and traditional uses of Echium amoenum. Pharmacognosy Reviews, 12: 208-213. https://doi.org/10.4103/phrev.phrev_13_18
Azizi, E., Salehan, N., Rahbarian, R. and Masoomi, A. (2024). Cytogenetic analysis of different landraces ofpurslane (Portulaca oleracea L.). Plant Genetic Research, 10(2): 35-46 (In Persian). https://doi.org/10.22034/PGR.10.2.3
Bonciu, E., Firbas, P., Fontanetti, C.S., Wusheng, J., Karaismailoğlu, M.C., Liu, D., Menicucci, F., Pesnya, D.S., Popescu, A. and Romanovsky, A.V. (2018). An evaluation for the standardization of the Allium cepa test as cytotoxicity and genotoxicity assay. Caryologia, 71: 191-209. https://doi.org/10.1080/00087114.2018.1503496
Bonciu, E., Firbas, P., Fontanetti, C.S., Wusheng, J., Karaismailoğlu, M.C., Liu, D., Menicucci, F., Pesnya, D.S., Popescu, A. and Romanovsky, A.V. (2018). An evaluation for the standardization of the Allium cepa test as cytotoxicity and genotoxicity assay. Caryologia, 71: 191-209. https://doi.org/10.1080/00087114.2018.1503496
Camparoto, M.L., Teixeira, R.O., Mantovani, M.S. and Vicentini, V.E.P. (2002). Effects of Maytenus ilicifolia Mart. and Bauhinia candicans Benth infusions on onion root-tip and rat bone-marrow cells. Genetics and Molecular Biology, 25: 85-89. https://doi.org/10.1590/S1415-47572002000100016
Chukwujekwu, J.C. and Van Staden, J. (2014). Cytotoxic and genotoxic effects of water extract of Distephanus angulifolius on Allium cepa Linn. South African Journal of Botany, 92: 147-150. https://doi.org/10.1016/j.sajb.2014.03.001
Daneshfar, E., Kuhkheil, A., Omidbaigi, R. and Zand, A. (2011). Vegetative and reproductive characteristics of Iranian Gole-Gav-Zaban (Echium amoenum Fisch & C. A. Mey) accessions cultivated in Mazandaran Province. Journal of American Science, 7: 911-913.
Das, A.B. and Roy, P. (1986). Cytological effects of some heavy metals on root meristems of Allium cepa L. Cytologia, 51(4): 793-801.
Das, R., Goswami, S., Ghosh, P., Roy, S. and Ray, S. (2022). Cytotoxic and cytostatic effects of leaf aqueous extract of Crinum asiaticum in Allium cepa root apical meristem cells. Cytologia, 87: 107-112. https://doi.org/10.1508/cytologia.87.107
Das, S.K. and Roy, S.K. (1989). Radio Cytologia studies on Solanum meiotic abnormalities. Cytologia, 54: 477-481. https://doi.org/10.1508/cytologia.54.477
Fiskesjo, G. (1985). The Allium test as a standard in environmental monitoring. Hereditas, 102: 99-112. https://doi.org/10.1111/j.1601-5223.1985.tb00471.x
Fukui, K. and Nakayama, S. (1996). Plant chromosomes: Laboratory methods. CRC Press, Boca Raton, Florida, USA.
Gali-Muhtasib, H. and Bakkar, N. (2002). Modulating cell cycle: current applications and prospects for future drug development. Current Cancer Drug Targets, 2: 309-336. https://doi.org/10.2174/1568009023333809
Hajmoradi, F. and Alijani, F. (2022). Chromosomal abnormalities induced by heavy metals in Golpar (Heracleum persicum Desf. ex fisch). Journal of Cellular and Molecular Research (Iranian Journal of Biology), 35: 1-10. (In Persian).
Hajmoradi, F and Kakaei, M. (2021). Genotoxic effects of heavy metals on mitotic chromosomes of Trigonella foenum-graecum L. Journal of Genetic Resource, 7(2): 264-270. https://doi.org/10.22080/jgr.2021.21814.1263
Ifeoma, O. and Oluwakanyinsola, S. (2013). Screening of herbal medicines for potential toxicities. In: Gowder, S.J.T. (Ed.), New insights into toxicity and drug testing, pp. 63-88. Intech Open Limited, London, UK. https://doi.org/10.5772/54493
Iqbal, M., Abbas, M., Nazir, A. and Qamar, A. (2019). Bioassays based on higher plants as excellent dosimeters for ecotoxicity monitoring: A review. Chemistry International, 5(1): 1-80.
Jamnani, M.J., Holmelid, B., Vedeler, A., Parsian, H.H., Andersen, H.L. and Fossen, T. (2023). Natural Products from Leaves of the Ancient Iranian Medicinal Plant Echium amoenum Fisch. & C. A. Mey. Molecules, 28: 385. https://doi.org/10.3390/molecules28010385
Jayathilake, N.J. and Jayewardena, U.A. (2021). Genotoxic potential of aqueous extract: A sea cucumber species, Bohadschia vitiensis using genotoxicity model Allium cepa. Advances in Pharmaceutical Journal, 6: 9-14. https://doi.org/10.31024/apj.2021.6.1.2
Kalidoss, A. and Krishnamoorthy, P. (2011). Antioxidant efficacy of endocarp with kernel of Ziziphus mauritiana Lam. in p-dimethylaminoazobenzene induced hepatocarcinoma in Rattus norvigicus. Indian Journal of Natural Products and Resources, 2: 387-314.
Kuruppuarachchi, S. U., Jayawardena, U. A. and Gunathilake, V. K. (2023). Use of the Allium cepa model to assess the cytogenotoxicity of luffariella herdmani marine sponge extract. Alternatives to Laboratory Animals, 51: 175-187. https://doi.org/10.1177/02611929231171943
Leme, D.M. and Marin-Morales, M.A. (2020). Allium cepa test in environmental monitoring: a review on its application. Mutation Research, 682: 71-81. https://doi.org/10.1016/j.mrrev.2009.06.002
Levan, A. (1938). The effect of colchicine on root mitoses in Allium. Hereditas, 24: 471-486. https://doi.org/10.1111/j.1601-5223.1938.tb03221.x
Levan, A. (1951). Localised chromosome breakage in Vicia faba. Hereditas, 30: 382-388.
Mansuell, R.W., Tanimoto, E.Y., Brown, C. and Comai, L. (1995). Irregular meiosis in a somatic hybrid between Solanum bulbocastanum and S. tuberosum detected by species-specific PCR markers and cytological analysis. Theoretical and Applied Genetics, 91: 401-408. https://doi.org/10.1007/BF00222966
Moustafa, M.F., Alrumman, S.A., Zaki, H., Loutfy, N. and Hashem, M. (2016). Cyto-physiological effects of aqueous extracts of some weeds and clove on the growth of Chinese faba bean (Vicia faba L.). Journal of Advances in Biology and Biotechnology, 9: 1-8. https://doi.org/10.9734/JABB/2016/27964
Owolarafe, T.A., Salawu, K., Ihegboro, G.O., Ononamadu, Ch.J., Alhassan, A.J. and Wudil, A.M. (2020). Investigation of cytotoxicity potential of different extracts of Ziziphus mauritiana (Lam) leaf Allium cepa model. Toxicology Reports, 7: 816-821. https://doi.org/10.1016/j.toxrep.2020.06.010
Pandey, H., Kumar, V. and Roy, B.K. (2014). Assessment of genotoxicity of some common food preservatives using Allium cepa L. as a test plant. Toxicology Reviews, 1: 300-308. https://doi.org/10.1016/j.toxrep.2014.06.002
Patocka, J. and Navratilova, Z. (2019). Bioactivity of Echium amoenum: a mini review. Biomedical Journal of Scientific and Technical Research, 20: 14915-14917. https://doi.org/10.26717/BJSTR.2019.20.003429
Prajitha, V. and Thoppil, J.E. (2016). Genotoxic and antigenotoxic potential of the aqueous leaf extracts of Amaranthus spinosus L. using Allium cepa assay. South African Journal of Botany, 102: 18-25. https://doi.org/10.1016/j.sajb.2015.06.018
Rechinger, K.H. (1967). Flora Iranica. Akademische Druck- und Verlagsanstalt, Graz, Austria.
Sandeep, W., Omkar, D., Harshada, M., Aaditi, P., Prajwal, G., Deepak, G., Nilesh, G., Ajay, K. and Mohan, K. (2021). Evaluation of phytochemical & antimitotic potential of annona reticulata extracts by onion root model. Chemical Proceedings, 3: 137. https://doi.org/10.3390/ecsoc-24-08296
Sehgal, R., Roy, S. and Kumar, V.L. (2006). Evaluation of cytotoxic potential of latex of Calotropis procera and podophyllotoxin in Allium cepa root model. Biocell, 30: 9-13. https://doi.org/10.32604/biocell.2006.30.009
Ślusarczyk, J., Dudek, M., Wierzbicka, M., Suchocki, P. and Kuraś, M. (2014). Antimitotic effect of Selol and sodium selenate (IV) on Allium test cells. Caryologia, 67: 250-259. https://doi.org/10.1080/0144235X.2014.974353
Soliman, M.I. (2001). Genotoxicity testing of neem plant (Azadirachta indica A. Juss.) using the Allium cepa chromosome aberration assay. Journal of Biological Sciences, 1: 1021-1027. https://doi.org/10.3923/jbs.2001.1021.1027
Sreeranjini, S. and Siril, E.A. (2011). Evaluation of anti-genotoxicity of the leaf extracts of Morinda citrifolia L. Plant, Soil and Environment, 57: 222-227. https://doi.org/10.17221/376/2010-PSE
Sudhakar, R., Gowda, N. and Venu, G. (2001). Mitotic abnormalities induced by silk dyeing industry effluents in the cells of Allium cepa. Cytologia, 66: 235-239. https://doi.org/10.1508/cytologia.66.235
Sunmonu, T.O., Oloyede, O.B., Owolarafe, T.A., Yakubu, M.T. and Dosunmu, O.O. (2014). Toxicopathological evaluation of Picralima nitida seed aqueous extract in Wistar rats. Turkish Journal of Biochemistry, 39: 119-125. https://doi.org/10.5505/tjb.2014.83997
Tamokou, J.D.D. and Kuete, V. (2014). Mutagenicity and carcinogenicity of African medicinal plants. In: Kuete, V. (Ed.), Toxicological survey of African medicinal plants, pp. 277-322. Elsevier, Amsterdam, Netherlands. https://doi.org/10.1016/B978-0-12-800018-2.00010-8
Tedesco, S.B. and Laughinghouse IV, H.D. (2012). Bioindicator of genotoxicity: The Allium cepa test. In: Srivastava, J.K. (Ed.), Environmental contamination, pp. 137-156. Intech Open Limited, London, UK.
Timothy, O., Idu, M. and Olorunfemi, D.I.(2014). Cytotoxic and genotoxic properties of leaf extract of Icacina trichantha Oliv. South African Journal of Botany, 91: 71-74. https://doi.org/10.1016/j.sajb.2013.11.008
Turkoglu, S. (2009). Genotoxic effects of mono-, di-, and trisodium phosphate on mitotic activity, DNA content, and nuclear volume in Allium cepa L. Caryologia, 62(3): 171-179. https://doi.org/10.1080/00087114.2004.10589683
Udo, I.J., Akpan, G.A. and Esenowo, I.K. (2014). Cytotoxic effects of (5) medicinal plants on mitosis in Allium cepa root tips. Current Research Journal of Biological Sciences, 6: 71-75. https://doi.org/10.19026/crjbs.6.5501
Wilson, G.B. (1945). The venetian turpentine mounting medium. Stain Technology, 20: 133-135. https://doi.org/10.3109/10520294509107150
Yuet Ping, K., Darah, I., Yusuf, U.K., Yeng, C. and Sasidharan, S. (2012). Genotoxicity of Euphorbia hirta: an Allium cepa assay. Molecules, 17: 7782-7791. https://doi.org/10.3390/molecules17077782
Zarei, P., Badakhshan, H. and Mirzaghaderi, G. (2024). Comparison of genetic diversity between two oat species (Avena sativa and Avena fatua) using phenotyping, molecular markers, and chromosomal parameters. Plant Genetic Research, 11(1): 15-36 (In Persian). https://doi.org/10.22034/PGR.11.1.2
